Unusual presentation of malignant phyllodes tumor in a young female: (Case report and review of literatures) malignant phyliodes tumor in adolesent.

Main Article Content

Hind Al-hashemi
Saad Abdulbaqi Alomar
sawsan Al-Haroon

Keywords

, phyllodes tumor, , Adolesence, malignant tumor, brest tumors

Abstract

SUMMARY:


Phyllodes tumor (PT) of the breast is rare in adolescent females, particularly malignant ones. It usually occurs in middle aged and older women. Malignant phyllodes (MP) do have a recurrence and a metastatic potential, unlike benign or borderline PT. We present the case of a 16-years old female presenting with a 6- month history of a progressive enlarged left breast mass. Tumor was excised as a mass of 7 cm in maximum diameter and sent for histopathological examination. The Histopathology revealed features of malignant phyllodes tumor that were confirmed by immunohistochemistry.

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References

1- Chen, Wei-Hsin . A rare presentation of malignant phyllodes tumor with bloody nipple discharge—report of a case. Gland Surgery 2017; 6(4), 412–416.
2- Sheppard, S., Shah, R., Madrigrano, A., & Kopkash, K. Malignant Phyllodes: A Presentation of Two Patients with a Rare Disease. The American Surgeon 2017; 83(12), 478-479.‏
3- Mills, S. E., Greenson, J. K., Hornick, J. L., Longacre, T. A., & Reuter, V. E. Sternberg's diagnostic surgical pathology, 6th ed. Lippincott Williams & Wilkins:1154-1159;2015.‏
4- Martino, A., Zamparelli, M., Santinelli, A., Cobellis, G., Rossi, L., & Amici, G. Unusual clinical presentation of a rare case of phyllodes tumor of the breast in an adolescent girl. Journal of pediatric surgery 2001; 36(6), 941-943.‏.
5- Collin, Y., Chagnon, F., Mongeau, C. J., Gonzalez-Amaya, G. L., & Sideris, L. Adrenal metastasis of a phyllodes tumor of the breast: case report and review of the literature. International Journal of Surgery Case Reports 2013; 4(8), 687-689.‏
6- Joshua J.X. Li. Fibroepithelial tumors, Phyllodes tumor [online]. Available from: https://www.pathologyoutlines.com/topic/breastphyllodesgeneral.html. Accessed date in 2/5/2022 at 6 p.m.
7- Fede, Â. B. D. S., Pereira Souza, R., Doi, M., De Brot, M., Aparecida Bueno de Toledo Osorio, C., Rocha Melo Gondim, G., …& Moraes Sanches, S. Malignant phyllodes tumor of the breast: a practice review. Clinics and practice 2021; 11(2), 205-215.‏
8- Feig, B. W., Berger, D. H., & Fuhrman, G. M. (Eds.). The MD Anderson surgical oncology handbook, 4th ed. Lippincott Williams & Wilkins: 57;2006.
9- Schnitt, S. J., & Collins, L. C. Biopsy interpretation of the breast, 3rd ed. Lippincott Williams & Wilkins, Philadelphia: 166-178;2009.
10- Gibbs Jr, B. F., Roe, R. D., & Thomas, D. F. Malignant cystosarcoma phyllodes in a pre-pubertal female. Annals of Surgery 1968; 167(2), 229-231.‏
11- Obafunwa, JO & Nwana, E. J. C. Malignant cystosarcoma phyllodes: report of two cases. Central African journal of medicine 1989; 35(10), 510-513.‏
12- Leveque, J., Meunier, B., Wattier, E., Burtin, F., Grall, J. Y., & Kerisit, J. Malignant cystosarcomas phyllodes of the breast in adolescent females. European Journal of Obstetrics & Gynecology and Reproductive Biology 1994; 54(3), 197-203.‏
13- Olugbenga, S., Isichei, M., & Isichei, C. Malignant Phyllodes Tumour in a Non-Governmental Health Centre (Faith Alive Foundation) in Jos, Plateau State North Central Nigeria. A Case Report and Review of Literature. Jos Journal of Medicine 2011; 5(2), 50-53.‏
14- Mills, A. M., & Showalter, S. L. Malignant Phyllodes Tumor of the Breast: A Case Study. Clinical Journal of Oncology Nursing 2014; 18(5), 595–597.
15- Athamnah, M. N., Abuelaish, O. M., & Rabai, N. A. Multifocal intra-parenchymal and sub-pectoral malignant phyllodes tumor in young female, rare and unusual presentation: a case report. International Journal of Surgery Case Reports 2020; 71, 280-284.‏
16- Makar, G. S., Makar, M., Ghobrial, J., Bush, K., Gruner, R. A., & Holdbrook, T. Malignant phyllodes tumor in an adolescent female: A rare case report and review of the literature. Case Reports in Oncological Medicine 2020; 1-7.‏
17- Saad, M. K., El Hajj, I., & Saikaly, E. Large Malignant Phyllodes Tumor of the Breast: Case Report of a Young Female and Review of Literature. Archives of Breast Cancer 2020; 137-146.‏
18- Muhammad, I. M., Musa, A. Gombe, A. A. A rare case of giant malignant phyllodes tumour and long term survival. Kanem Journal of Medical Sciences 2021; 15(2), 132 – 135.
19- Shaukat, U., Rehman, U., Younis, M. N., & Shahid, A. Malignant Phyllodes Breast Tumor: A Rare Case of Metastasis in Skeletal Muscle Detected on 18-Fluorodeoxyglucose Positron

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